2008, ISBN: 9780123740281

Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and ma… More...

Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of neurodegeneration, as well as therapeutic approaches. In this book, the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in cell death will be described, as well as the opportunities that these systems provide in drug discovery. Buch (fremdspr.) Serge Przedborski#Nass gebundene Ausgabe, Academic Press, 01.07.2008, Academic Press, 2008<

2008, ISBN: 9780123740281

Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and ma… More...

Parkinson's disease is the second most prevalent neurodegenerative disease and is characterized by the irreversible loss of dopamine neurons. Despite its high prevalence in society and many decades of research, the origin of the pathogenesis and the molecular determinants involved in the disorder has remained elusive. Confounding this issue is the lack of experimental models that completely recapitulate the disease state. The identification of a number of genes thought to play a role in cell death, and development of both toxin and genetic models to explore the function of the genes both in unaffected and diseased cells are now providing new insights into the molecular basis of neurodegeneration, as well as therapeutic approaches. In this book, the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in cell death will be described, as well as the opportunities that these systems provide in drug discovery. Buch (fremdspr.) Nass#Serge Przedborski gebundene Ausgabe, Academic Press, 01.07.2008, Academic Press, 2008<

ISBN: 9780123740281

Hardback, [PU: Elsevier Science Publishing Co Inc], Parkinson's disease is characterized by the irreversible loss of dopamine neurons. This title describes the advances and the advantages… More...

Hardback, [PU: Elsevier Science Publishing Co Inc], Parkinson's disease is characterized by the irreversible loss of dopamine neurons. This title describes the advances and the advantages that various invertebrates, cell culture, rodents, and mammals provide in the identification of the molecular components and mechanisms involved in the cell death., Neurology & Clinical Neurophysiology<

ISBN: 9780123740281

*Parkinson's Disease: Molecular and Therapeutic Insights from Model Systems* / gebundene Ausgabe für 153.49 € / Aus dem Bereich: Bücher, Wissenschaft, Medizin Medien > Bücher nein Buch (g… More...

*Parkinson's Disease: Molecular and Therapeutic Insights from Model Systems* / gebundene Ausgabe für 153.49 € / Aus dem Bereich: Bücher, Wissenschaft, Medizin Medien > Bücher nein Buch (gebunden) Bücher > Wissenschaft > Medizin, ACADEMIC PR INC<

2008, ISBN: 9780123740281

Molecular and Therapeutic Insights From Model Systems, Buch, Hardcover, [PU: Academic Press Inc], Academic Press Inc, 2008