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Chemical Mutagens : Principles and Methods for Their Detection: Volume 2 - Joel S. Hirschhorn
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Chemical Mutagens : Principles and Methods for Their Detection: Volume 2 - new book

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The best protection against environmental mutagens is to identify them before they ever come into general use.But it is always possible that some substance will escape detection and affec… More...

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Chemical Mutagens - Alexander Hollaender
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The best protection against environmental mutagens is to identify them before they ever come into general use. But it is always possible that some substance will escape detection and affe… More...

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Chemical Mutagens
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The best protection against environmental mutagens is to identify them before they ever come into general use. But it is always possible that some substance will escape detection and affe… More...

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Chemical Mutagens - Alexander Hollaender
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Chemical Mutagens - new book

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Biomedicine; Human Genetics; Bioorganic Chemistry; Veterinary Medicine/Veterinary Science Allele, DNA, Fixation, Hamster, Handling, Mamma, Salmonella, Termination, Tumor, chromosome, emer… More...

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Chemical Mutagens : Principles and Methods for Their Detection: Volume 2 - Granville Sewell
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; PDF; Scientific, Technical and Medical > Pre-clinical medicine: basic sciences > Medical genetics, Springer New York

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Chemical Mutagens
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9781461589693

Details of the book - Chemical Mutagens


EAN (ISBN-13): 9781461589693
Publishing year: 12
Publisher: Springer

Book in our database since 2015-07-08T08:15:43-04:00 (New York)
Detail page last modified on 2023-11-12T21:09:55-05:00 (New York)
ISBN/EAN: 9781461589693

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Book author: granville

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Author: Alexander Hollaender
Title: Chemical Mutagens - Principles and Methods for Their Detection: Volume 2
Publisher: Springer; Springer US
342 Pages
Publishing year: 2012-12-06
New York; NY
Language: English
96,29 € (DE)
99,00 € (AT)
118,00 CHF (CH)
Available
XXII, 342 p.

EA; E107; eBook; Nonbooks, PBS / Medizin/Klinische Fächer; Genetik, Medizin; Verstehen; Allele; DNA; Fixation; Hamster; Handling; Mamma; Salmonella; Termination; Tumor; chromosome; emergency; genes; hand; mutagen; mutation; C; Medical Genetics; Bioorganic Chemistry; Veterinary Science; Biomedical and Life Sciences; Organische Chemie; Biochemie; Tiermedizin; BC

of Volume 2.- 11 Measurement of Recessive Lethal Damage Over the Entire Genome and at Two Specific Loci in the ad-3 Region of a Two-Component Heterokaryon of Neurospora Crassa.- I. Introduction.- II. Measurement of the Genetic Effects of Mutagenic Treatment.- III. Characterization of Presumptive ad-3 Mutants.- IV. Media and Chemical Solutions.- V. References.- 12 Aspergillus.- I. Introduction.- II. Life Cycle and Genetic Analysis.- III. Mutation.- IV. Conclusions.- V. References.- 13 Higher Plants.- I. Introduction.- II. Test Systems.- III. Compounds Tested for Mutagenic Activity by Treatment of Seeds.- IV. Special Techniques That Have a Higher Resolving Power.- V. General Evaluation.- VI. Acknowledgments.- VII. References.- 14 Procedures for Culturing Diploid Cells and Preparation of Meiotic Chromosomes from Dwarf Species of Hamsters.- I. Introduction.- II. Background Information.- III. Handling the Diploid Cell.- IV. Spermatogonial and Meiotic Chromosome Preparations.- V. Bone Marrow Biopsy Procedure.- VI. Discussion.- VII. Acknowledgments.- VIII. References.- 15 Induction and Analysis of Gene Mutations in Mammalian Cells in Culture.- I. Introduction.- II. The Cell Material.- III. Utilization of In Vivo Markers.- IV. Detection of Recessive Mutations in Cell Cultures.- VI. Characterization of Newly Isolated Variants.- VII. Procedure for Mutation Induction.- VIII. Concluding Remarks.- IX. Acknowledgments.- X. References.- 16 Inducing Mutations with Chemicals in Habrobracon.- I. Introduction.- II. Maintenance of Habrobracon and Ephestia.- III. Scheme for Mutational Analysis.- IV. Application of Mutagens.- V. Conclusions.- VI. References.- 17 The Detection of Mutations in Drosophila melanogaster.- I. Introduction.- II. Advantages of Drosophila as a Test Organism.- III. Limitations of Drosophila as a Test Organism.- IV. Lethal Tests.- V. Tests for Recessive Visible Mutants.- VI. Tests for Chromosomal Rearrangements.- VII. Tests for Loss of X or Y Chromosomes.- VIII. Tests for Dominant Lethals.- IX. Tests for Half-Translocations.- X. Staging of Germ Cells.- XI. Techniques for Collecting Flies of a Desired Sex.- XII. Review of Literature.- XIII. Summary.- XIV. References.- 18 Root Tips for Studying the Effects of Chemicals on Chromosomes.- I. The Material.- II. Treatment of Root Tips with Chemicals.- III. Fixation and Staining of Root Tips.- IV. Scoring of Slides and Types of Aberration.- V. Comparison Between the Effects of Chemicals on Chromosomes in Root-Tip Cells and in Cultured Animal Cells.- VI. Acknowledgments.- VII. References.- VIII. Suggested Reading.- 19 Cytogenetic Studies in Animals.- I. Introduction.- II. Experimental Design.- III. Classification of Chromosomal Aberrations.- IV. Localization of Chromosomal Aberrations.- V. Timing of Chromosomal Damage.- VI. Meiotic Studies.- VII. In Vivo and in Vitro Studies.- VIII. Specific Techniques.- IX. Summary.- X. References.- 20 Specific Locus Mutation in Mice.- I. Introduction.- II. The Method, Its Advantages and Disadvantages.- III. Results Obtained.- IV. Conclusions.- V. References.- 21 Dominant Lethal Mutations in Mammals.- I. Introduction.- II. The Dominant Lethal Syndrome.- III. The Estimation of Dominant Lethals.- IV. The Genotypes of Dominant Lethals.- VI. Dominant Lethals in Female Germ Cells.- VII. General Validity of the Dominant Lethal Test.- VIII. Synergistic Effects.- IX. Review of Chemicals Tested as Dominant Lethal Mutagens in Mammals.- X. Integration of the Dominant Lethal Assay and Other Mutagenicity Tests into General Toxicological Practice.- XI. References.- 22 TheHost-Mediated Assay, a Practical Procedure for Evaluating Potential Mutagenic Agents in Mammals.- I. Introduction.- II. Materials and Methods.- III. Results.- IV. Conclusion.- V. References.- 23 Human Population Monitoring.- I. Introduction.- II. A Classification of Mutational Effects.- III. Criteria for a Mutation-Monitoring System.- IV. Some Ways of Amplifying the Mutation-Detecting Power of Monitoring Systems.- V. Monitoring for Germinal Mutations.- A. Monitoring for Dominant Mutant Phenotypes.- B. Biochemical Monitoring.- VI. Summary.- VII. References.- Conclusion.- Author Index.
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