ISBN: 9780471870326

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective dru… More...

On the cover of this book is a Pacific yew tree, found in the ancient forests of the Pacific Northwest. The bark of the Pacific yew tree produces Taxol, found to be a highly effective drug against ovarian and breast cancer. Taxol blocks mitosis during eukaryotic cell division. The supply of Taxol from the Pacific yew tree is vanishingly small, however. A single 100-year-old tree provides only about one dose of the drug (roughly 300 mg). For this reason, as well as the spectacular molecular architecture of Taxol, synthetic organic chemists fiercely undertook efforts to synthesize it. Five total syntheses of Taxol have thus far been reported. Now, a combination of isolation of a related metabolite from European yew needles, and synthesis of Taxol from that intermediate, supply the clinical demand. This case clearly demonstrates the importance of synthesis and the use of organic chemistry. It's just one of the many examples used in the text that will spark the interest of students and get them involved in the study of organic chemistry! Media > Book, [PU: Wiley]<

ISBN: 0471870323

[EAN: 9780471870326], Gebraucht, guter Zustand, [PU: Wiley], Spine creases, wear to binding and pages from reading. May contain limited notes, underlining or highlighting that does affect… More...

[EAN: 9780471870326], Gebraucht, guter Zustand, [PU: Wiley], Spine creases, wear to binding and pages from reading. May contain limited notes, underlining or highlighting that does affect the text. Possible ex library copy, that’ll have the markings and stickers associated from the library. Accessories such as CD, codes, toys, may not be included.<

ISBN: 9780471870326

Wiley. Hardcover. POOR. Noticeably used book. Heavy wear to cover. Pages contain marginal notes, underlining, and or highlighting. Possible ex library copy, with all the markings/sticke… More...

Wiley. Hardcover. POOR. Noticeably used book. Heavy wear to cover. Pages contain marginal notes, underlining, and or highlighting. Possible ex library copy, with all the markings/stickers of that library. Accessories such as CD, codes, toys, and dust jackets may not be included., Wiley<

ISBN: 0471870323

[EAN: 9780471870326], Gebraucht, sehr guter Zustand, [PU: Wiley], Light rubbing wear to cover, spine and page edges. Very minimal writing or notations in margins not affecting the text. P… More...

[EAN: 9780471870326], Gebraucht, sehr guter Zustand, [PU: Wiley], Light rubbing wear to cover, spine and page edges. Very minimal writing or notations in margins not affecting the text. Possible clean ex-library copy, with their stickers and or stamp(s).<

1984, ISBN: 0471870323

[EAN: 9780471870326], [PU: John Wiley & Sons Inc]