2008, ISBN: 9780387691183

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… More...

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<

2008, ISBN: 9780387691183

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to… More...

There is now a pressing need to discuss the already described and newly emerging mechanisms to see how they can be put together in more or less cohesive structure and how they can help to improve immune response to tumors. This monograph will, for the first time, present a comprehensive overview of different mechanisms of immune dysfunction in cancer as well as therapeutic approaches to their correction. It will discuss a number of new mechanisms that have never been discussed in a monograph before: T-cell inhibitory molecules, regulatory tolerogenic DCs, and signaling pathways in antigen-presenting cells involved in T-cell tolerance. TOC:Introduction.- Mechanisms and Therapeutic Reversal of the Defects in T-Cell Function in Cancer.- Molecular Mechanisms of Tumor-Associated T-Cell Tolerance.- T-Cell Tolerance.- T-Cell Inhibitory Molecules and Suppression of T-Cell Function In Cancer.- CTLA-4 and T-Cell Tolerance in Cancer.- Regulatory T-Cells in Cancer.- T-Cell Apoptosis in Cancer.- Defects in Dendritic Cell Differentiation in Cancer and Tumor Escape.- Dendritic Cells With Tolerogenic Potential in Cancer.- Signaling Pathways in Antigen-Presenting Cells Involved in Induction of T-Cell Tolerance.- Macrophages and Tumor Development.- Immature Myeloid Suppressor Cells in Tumor-Induced T-Cell Tolerance.- Arginin Metabolism as A Critical Element of Tumor Suppression in Cancer.- Role of Reactive Oxygen Species in T-Cell Defects in Cancer.- Cytokine Production in Cancer and their Negative Effect on Immune Response.- Inflammation and Immune Abnormalities in Cancer.- Tumor Stroma and Antitumor Immune Response.- Tumor Associated Immune Defects. Where are Now and Where are We Going. eBook Springer PDF, Springer, 01.01.2008, Springer, 2008<

ISBN: 9780387691183

Tumor-Induced Immune Suppression - Mechanisms and Therapeutic Reversal: ab 129.99 € eBooks > Fachthemen & Wissenschaft > Wissenschaften allgemein Springer-Verlag GmbH eBook als pdf, Sprin… More...

Tumor-Induced Immune Suppression - Mechanisms and Therapeutic Reversal: ab 129.99 € eBooks > Fachthemen & Wissenschaft > Wissenschaften allgemein Springer-Verlag GmbH eBook als pdf, Springer-Verlag GmbH<

ISBN: 0387691189

Tumor-Induced Immune Suppression ab 129.99 € als pdf eBook: . Aus dem Bereich: eBooks, Fachthemen & Wissenschaft, Medizin, Medien > Bücher, Tumor-Induced Immune Suppression

ISBN: 0387691189

Tumor-Induced Immune Suppression ab 129.99 EURO Medien > Bücher, [PU: Springer]