2010, ISBN: 9781617374937

[ED: Softcover], [PU: Humana / Humana Press / Springer, Berlin], A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods ran… More...

[ED: Softcover], [PU: Humana / Humana Press / Springer, Berlin], A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using nonviral (polymers, liposomes, and antisense agents) and adenoviral vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. The book offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success. Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success. 2010. xvi, 502 S. XVI, 502 p. 98 illus. 229 mm Versandfertig in 6-10 Tagen, DE, Neuware, gewerbliches Angebot, Offene Rechnung (Vorkasse vorbehalten)<

2010, ISBN: 1617374938

[EAN: 9781617374937], Neubuch, [SC: 18.32], [PU: SPRINGER NATURE], MEDICAL / NURSING; CARDIOLOGY; SCIENCE GENERAL, Druck auf Anfrage Neuware - Printed after ordering - A collection of new… More...

[EAN: 9781617374937], Neubuch, [SC: 18.32], [PU: SPRINGER NATURE], MEDICAL / NURSING; CARDIOLOGY; SCIENCE GENERAL, Druck auf Anfrage Neuware - Printed after ordering - A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using nonviral (polymers, liposomes, and antisense agents) and adenoviral vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. The book offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success. Our understanding of the pathogenesis of hypertension and the development of new therapies for its management have each proven to be directly dependent on the availability and application of novel molecular biological methodologies. In Hypertension: Methods and Protocols, a panel of recognized experts from key institutions around the world describes in step-by-step detail many new and essential molecular techniques for cardiovascular hypertension research. The methods presented range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic material using adenoviral and nonviral (polymers, liposomes, and antisense agents) vectors. Additional techniques described include single nucleotide polymorphism (SNP) genotyping, RNA interference, microarray analysis, pharmacogenetics, and pharmacogenomics for the genetic dissection of hypertension, as well as a practical method for deriving cardiomyocytes from embryonic stem cells that would serve as replacement cells for those damaged by hypertension or heart attack. A review of bioinformatic resources for pharmacogenomics describes the application of in silico strategies to identify nuclear matrix attachment regions. The protocols follow the successful Methods in Molecular Medicine series format, each offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.State-of-the-art and highly practical, Hypertension: Methods and Protocols offers both novice and experienced hypertension researchers an indispensable collection of readily reproducible techniques for successful research, work that has already dramatically improved the outlook for hypertensive patients, and promises much future success. 502 pp. Englisch, Books<

2010, ISBN: 1617374938

[EAN: 9781617374937], Neubuch, [PU: Humana Press], MEDICAL NURSING CARDIOLOGY SCIENCE GENERAL BLOOD PRESSURE CARDIOVASCULAR GENE THERAPY GENETICS HEART HYPERTENSION VASCULAR DISEASE HERZ-… More...

[EAN: 9781617374937], Neubuch, [PU: Humana Press], MEDICAL NURSING CARDIOLOGY SCIENCE GENERAL BLOOD PRESSURE CARDIOVASCULAR GENE THERAPY GENETICS HEART HYPERTENSION VASCULAR DISEASE HERZ- UND GEFÄSSMEDIZIN INTERNAL MEDICINE, Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods range widely from producing congenic, consomic, transgenic, and knockout models of hypertension to the gene transfer of specific genetic m., Books<

2010, ISBN: 9781617374937

Paperback

[ED: Kartoniert / Broschiert], [PU: Humana Press], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A collection of new and essential molec… More...

[ED: Kartoniert / Broschiert], [PU: Humana Press], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. A collection of new and essential molecular techniques for cardiovascular research. These readily reproducible methods range widely from producing congenic, con, DE, [SC: 0.00], Neuware, gewerbliches Angebot, Taschenbuch, 502, [GW: 753g], 1. Auflage, Banküberweisung, PayPal, [CT: Medizin/Pharmazie / Sonstiges - Medizin]<

2010, ISBN: 9781617374937

Methods and Protocols, Buch, Softcover, Softcover reprint of hardcover 1st ed. 2005, [PU: Humana Press Inc.], Humana Press Inc., 2010