ISBN: 9781607614463

Efforts to describe and model the molecular structure of biological membranes go back to the beginning of the last century. In 1917, Langmuir described membranes as a layer of lipids one … More...

Efforts to describe and model the molecular structure of biological membranes go back to the beginning of the last century. In 1917, Langmuir described membranes as a layer of lipids one molecule thick [1]. Eight years later, Gorter and Grendel concluded from their studies that “the phospholipid molecules that formed the cell membrane were arranged in two layers to form a lipid bilayer” [2]. Danielli and Robertson proposed, in 1935, a model in which the bilayer of lipids is sequestered between two monolayers of unfolded proteins [3], and the currently still accepted fuid mosaic model was proposed by Singer and Nicolson in 1972 [4]. Among those landmarks of biomembrane history, a serendipitous observation made by Alex Bangham during the early 1960s deserves undoubtedly a special place. His fnding that exposure of dry phospholipids to an excess of water gives rise to lamellar structures [5] has opened versatile experimental access to studying the biophysics and biochemistry of biological phospholipid membranes. Although during the following 4 decades biological membrane models have grown in complexity and functionality [6], liposomes are, besides supported bilayers, membrane nanodiscs, and hybrid membranes, still an indisputably important tool for membrane b- physicists and biochemists. In vol. II of this book, the reader will fnd detailed methods for the use of liposomes in studying a variety of biochemical and biophysical membrane phenomena concomitant with chapters describing a great palette of state-of-the-art analytical technologies., Humana<

2009, ISBN: 1607614464

With nearly one hundred years of intensive study, lipids have proven to be a vital and ever-more-promising area of cell biological research. In Liposomes: Methods and Protocols, leading e… More...

With nearly one hundred years of intensive study, lipids have proven to be a vital and ever-more-promising area of cell biological research. In Liposomes: Methods and Protocols, leading experts in the related fields explore cutting-edge experimental methods involving all aspects of lipids as essential components of the cell membrane. Volume 2: Biological Membrane Models focuses on detailed methods for the use of liposomes in studying a variety of biochemical and biophysical membrane phenomena concomitant with chapters describing a great palette of state-of-the-art analytical technologies. As a volume in the highly successful Methods in Molecular Biology(TM) series, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Liposomes: Methods and Protocols promises to be an essential source of practical know-how for every investigator, young and seasoned alike, whose research area involves in one way or another phospholipids, glycolipids, or cholesterol. Media Buch, 548 Seiten, Media > Books, Humana Press, 2009<

2009, ISBN: 9781607614463

Editor: Weissig, Volkmar, Humana, Hardcover, Auflage: 2010, 564 Seiten, Publiziert: 2009-12-23T00:00:01Z, Produktgruppe: Book, 1.37 kg, Textbook Rental ASINs, Specialty Stores, Books, Bio… More...

Editor: Weissig, Volkmar, Humana, Hardcover, Auflage: 2010, 564 Seiten, Publiziert: 2009-12-23T00:00:01Z, Produktgruppe: Book, 1.37 kg, Textbook Rental ASINs, Specialty Stores, Books, Biochemistry, Biological Sciences, Science & Math, Subjects, Cell Biology, Molecular Biology, Pharmacology, Medical Books, Basic Sciences, Medicine & Health Sciences, New, Used & Rental Textbooks, Specialty Boutique, Biology & Life Sciences, Science & Mathematics, Humana, 2009<

2009, ISBN: 1607614464

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