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Steven L. Peterson (Editor), Timothy E. Albertson (Editor):
Neuropharmacology Methods in Epilepsy Research - new book

ISBN: 9780849333620

There is an estimated 2.5 million epileptics in the US and perhaps some 40 million worldwide. As research has become increasingly molecular in scope, fewer scientists are trained in the US on basic, integrated epilepsy techniques. One frustration in neuroscience today is the application of state-of-the-art molecular biology techniques to inappropriate animal models of epilepsy - frequently resulting in inconclusive results. Epilepsy research will be increasingly undertaken by scientists well-trained in reductionist methodology, but who may be unfamiliar with integrated, whole-animal techniques. This situation appears even more difficult considering there has been no updated textbook on experimental models of epilepsy over the last twenty years - until now.Neuropharmacology Methods in Epilepsy Research describes fundamental methodologies and procedures in this field, representing the only detailed text concerning experimental models of epilepsy published in the last 20 years. This guide studies the reproduction of well-characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied.Each chapter features:Introduction - providing a brief background and historical account of the techniques and their useMethodology - describing equipment, solutions, species, electrodes as well as considering variations of techniques and stimulation parametersInterpretations - demonstrating the relevance of techniques to epilepsy as well as describing what exactly is being studied and how the data is appropriately applied to understanding epilepsyTopics include electroshock, chemoconvulsions, kindling, audiogenic seizures, focal seizures, and brain slice preparations.Discussions also include:Recently developed seizure models, including status epilepticus and massed trial simulationsInfluence of circadian and diurnal rhythms on Textbooks New Books ~~ Professional Medical & Health Sciences ~~ Neuroscience - Pharmacology Neuropharmacology-Methods-in-Epilepsy-Research~~Steven-L-Peterson CRC Press Methods in Epilepsy Research is a guide for the reproduction of well characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. It also considers the appropriate application of reductionist techniques to experimental models of epilepsy. TOC:Electroshock. - Chemoconvulsions. - Kindling. - Brain Slice Preparation for Epilepsy Research. - In Vivo Massed Trial Stimulations. - Audiogenic Seizures in the Mouse and Genetically Epilepsy-Prone Rat. - Focal Seizures. - Evaluation of Behavioural Cognitive Deficits Associated With Antiepileptic Drugs. - Diurnal and Circadian Influences on Seizure Response. - Microdialysis Techniques of Epilepsy Research. - Automated EEG Analyses. - Status Epilepticus. - Focal Microinfusions and Consideration of Neuronal Networks in Epilepsy Research. - Genetic Models of Epilepsy.

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Peterson, Steven Lloyd:
Neuropharmacology Methods in Epilepsy Research - Paperback

1998, ISBN: 0849333628, Lieferbar binnen 4-6 Wochen Shipping costs:Versandkostenfrei innerhalb der BRD

ID: 9780849333620

Internationaler Buchtitel. In englischer Sprache. Verlag: CRC PR INC, 304 Seiten, L=232mm, B=154mm, H=16mm, Gew.=435gr, [GR: 26960 - TB/Medizin/Andere Fachgebiete], [SW: - Medical / Nursing], Kartoniert/Broschiert, Klappentext: Methods in Epilepsy Research is a guide for the reproduction of well characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. It also considers the appropriate application of reductionist techniques to experimental models of epilepsy. TOC:Electroshock. - Chemoconvulsions. - Kindling. - Brain Slice Preparation for Epilepsy Research. - In Vivo Massed Trial Stimulations. - Audiogenic Seizures in the Mouse and Genetically Epilepsy-Prone Rat. - Focal Seizures. - Evaluation of Behavioural Cognitive Deficits Associated With Antiepileptic Drugs. - Diurnal and Circadian Influences on Seizure Response. - Microdialysis Techniques of Epilepsy Research. - Automated EEG Analyses. - Status Epilepticus. - Focal Microinfusions and Consideration of Neuronal Networks in Epilepsy Research. - Genetic Models of Epilepsy. Methods in Epilepsy Research is a guide for the reproduction of well characterized and readily interpretable experimental models of epilepsy to which state-of-the-art molecular biology techniques can be applied. It also considers the appropriate application of reductionist techniques to experimental models of epilepsy. TOC:Electroshock. - Chemoconvulsions. - Kindling. - Brain Slice Preparation for Epilepsy Research. - In Vivo Massed Trial Stimulations. - Audiogenic Seizures in the Mouse and Genetically Epilepsy-Prone Rat. - Focal Seizures. - Evaluation of Behavioural Cognitive Deficits Associated With Antiepileptic Drugs. - Diurnal and Circadian Influences on Seizure Response. - Microdialysis Techniques of Epilepsy Research. - Automated EEG Analyses. - Status Epilepticus. - Focal Microinfusions and Consideration of Neuronal Networks in Epilepsy Research. - Genetic Models of Epilepsy.

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Steven L. Peterson; T. E. Albertson:
Neuropharmacology Methods in Epilepsy Research - Paperback

1998, ISBN: 9780849333620

ID: 591805

Softcover, Buch, [PU: Crc Press Inc]