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Concepts, Mechanisms, and New Targets for Chemotherapy - Franco M. Muggia (Editor)
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Franco M. Muggia (Editor):
Concepts, Mechanisms, and New Targets for Chemotherapy - new book

ISBN: 9780792335252

The book contains black-and-white illustrations. Textbooks New Books ~~ Medicine~~ Oncology Concepts-Mechanisms-and-New-Targets-for-Chemotherapy~~Franco-M-Muggia Springer US Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity. Modification of existing therapies based on the pursuit of leads arising from mechanistic studies is also being applied clinically on a wide scale. Greater understanding should follow from the studies of reversal of the multidrug resistant phenotype, on the use of hydroxyurea to reverse resistance mediated by extrachromosomal DNA, and on various aspects of the fluoropyrimidine pathways. Successful applications of chemotherapy to the treatment of specific diseases include the growing applications of systemic therapy using various skin malignancies. In prostate cancer, estramustine phosphate will likely play an expanding role. Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers.

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Concepts, Mechanisms, and New Targets for Chemotherapy
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Concepts, Mechanisms, and New Targets for Chemotherapy - new book

ISBN: 9780792335252

ID: 978079233525

Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity. Modification of existing therapies based on the pursuit of leads arising from mechanistic studies is also being applied clinically on a wide scale. Greater understanding should follow from the studies of reversal of the multidrug resistant phenotype, on the use of hydroxyurea to reverse resistance mediated by extrachromosomal DNA, and on various aspects of the fluoropyrimidine pathways. Successful applications of chemotherapy to the treatment of specific diseases include the growing applications of systemic therapy using various skin malignancies. In prostate cancer, estramustine phosphate will likely play an expanding role. Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers. Books, Health and Well Being, Concepts, Mechanisms, and New Targets for Chemotherapy Books>Health and Well Being, Springer US

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Concepts, Mechanisms and New Targets for Chemotherapy - Franco M. Muggia
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Franco M. Muggia:
Concepts, Mechanisms and New Targets for Chemotherapy - hardcover

ISBN: 9780792335252

Hardback, [PU: Kluwer Academic Publishers], Describes new interconnections between rationally designed and empirically discovered compounds. This book includes a summary of the status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity., Chemotherapy

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Concepts Mechanisms and New Targets for Chemotherapy - Franco M. Muggia
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Franco M. Muggia:
Concepts Mechanisms and New Targets for Chemotherapy - new book

ISBN: 9780792335252

ID: 9780792335252

Concepts Mechanisms and New Targets for Chemotherapy Author :Franco M. Muggia 9780792335252 0792335252, [PU: Kluwer Academic Publishers]

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Concepts, Mechanisms, and New Targets for Chemotherapy - Franco M  Muggia
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Franco M Muggia:
Concepts, Mechanisms, and New Targets for Chemotherapy - new book

ISBN: 9780792335252

ID: 467775332

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Details of the book
Concepts, Mechanisms, and New Targets for Chemotherapy

Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity. Modification of existing therapies based on the pursuit of leads arising from mechanistic studies is also being applied clinically on a wide scale. Greater understanding should follow from the studies of reversal of the multidrug resistant phenotype, on the use of hydroxyurea to reverse resistance mediated by extrachromosomal DNA, and on various aspects of the fluoropyrimidine pathways. Successful applications of chemotherapy to the treatment of specific diseases include the growing applications of systemic therapy using various skin malignancies. In prostate cancer, estramustine phosphate will likely play an expanding role. Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers.

Details of the book - Concepts, Mechanisms, and New Targets for Chemotherapy


EAN (ISBN-13): 9780792335252
ISBN (ISBN-10): 0792335252
Hardcover
Publishing year: 1995
Publisher: SPRINGER VERLAG GMBH
256 Pages
Weight: 0,526 kg
Language: eng/Englisch

Book in our database since 11.05.2007 08:38:26
Book found last time on 26.10.2017 17:15:13
ISBN/EAN: 0792335252

ISBN - alternate spelling:
0-7923-3525-2, 978-0-7923-3525-2


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