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Modulation of Protein Stability in Cancer Therapy - Eric Rubin
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Eric Rubin:
Modulation of Protein Stability in Cancer Therapy - new book

ISBN: 9780387691473

ID: 9780387691473

Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von HippelLindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs. Modulation of Protein Stability in Cancer Therapy: Over the past two decades, there has been a tremendous increase in our understa- ing of ubiquitination and proteasome degradation. As the editors, we thank Springer Publishing for allowing us to organize this collection of reviews on the ubiquit- proteasome system, oncogenesis, and cancer therapy. We asked our colleagues, who are experts in the field, to provide an overview of their research and recent progress. Each chapter covers a broad range of topics that include defects in ubiquitination identified in specific tumors to new directions to treat cancer. In the Introduction, Rati Verma gives the background of our current understanding of the proteasome. A general overview of ubiquitin ligases and cancer is provided by Angelika Burger and Arun Seth. Patricia McChesney and Gary Kupfer discuss the role of the Fanconi anemia/BRCA1 pathways in breast cancer and potential targets for therapy. Defects in the tumor suppressor, von HippelLindau E3 ligase, and the role of this protein complex are discussed by William Kim and William Kaelin. Kyung-bo Kim and colleagues describe the development of novel proteasome inhibitors to treat cancer patients. Progress in our understanding of deubiquitinating enzymes is summarized by Massimo Loda and his colleagues. Finally, Agustin Rodriguez-Gonzalez and Kathleen Sakamoto discuss an approach to recruit cancer-causing proteins to ub- uitin ligases through a chimeric molecule known as protacs., Springer-Verlag Gmbh

New book Rheinberg-Buch.de
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Modulation of Protein Stability in Cancer Therapy - Sakamoto, Kathleen; Rubin, Eric
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Sakamoto, Kathleen; Rubin, Eric:
Modulation of Protein Stability in Cancer Therapy - new book

2009, ISBN: 0387691472

ID: 9780387691473

In englischer Sprache. Verlag: Springer New York, This comprehensive monograph on the role of protein modulation in cancer therapeutics focuses on targeting molecules that regulate protein stability in a variety of tumors. Topics covered include ubiquitin ligases, deubiquitinating enzymes, and the proteasome. PC-PDF, 165 Seiten, X Seiten, 165 Seiten, [GR: 9692 - Nonbooks, PBS / Medizin/Nichtklinische Fächer], [SW: - Vorklinische Medizin, Grundlagenwissenschaften], [Ausgabe: 2009][PU:Springer New York], [PU: Springer]

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Modulation of Protein Stability in Cancer Therapy - Kathleen Sakamoto; Eric Rubin
book is out-of-stock
(*)
Kathleen Sakamoto; Eric Rubin:
Modulation of Protein Stability in Cancer Therapy - new book

ISBN: 9780387691473

ID: 9780387691473

Biomedicine; Cancer Research; Medical Microbiology; Human Genetics; Immunology; Biochemistry, general BRCA, anemia, carcinogenesis, enzymes, prostate cancer, protein, proteins Books eBook, Springer Science+Business Media

New book Springer.com
This comprehensive monograph on the role of protein modulation in cancer therapeutics focuses on targeting molecules that regulate protein stability in a variety of tumors. Topics covered include ubiquitin ligases, deubiquitinating enzymes, and the protea Shipping costs: EUR 0.00
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Modulation of Protein Stability in Cancer Therapy - Eric Rubin;  Kathleen Sakamoto;  Eric Rubin;  Kathleen Sakamoto
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Eric Rubin; Kathleen Sakamoto; Eric Rubin; Kathleen Sakamoto:
Modulation of Protein Stability in Cancer Therapy - First edition

2009, ISBN: 9780387691473

ID: 21671119

[ED: 1], Auflage, eBook Download (PDF), eBooks, [PU: Springer-Verlag]

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Modulation of Protein Stability in Cancer Therapy - Kathleen Sakamoto; Eric Rubin
book is out-of-stock
(*)
Kathleen Sakamoto; Eric Rubin:
Modulation of Protein Stability in Cancer Therapy - First edition

2009, ISBN: 9780387691473

ID: 21671119

[ED: 1], eBook Download (PDF), eBooks, [PU: Springer New York]

New book Lehmanns.de
Shipping costs:Download sofort lieferbar, , Versandkostenfrei innerhalb der BRD (EUR 0.00)
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