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Chemical Carcinogenesis - Joann Cleland
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Chemical Carcinogenesis - new book

ISBN: 9781617379956

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many ca… More...

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Chemical Carcinogenesis - Trevor M. Penning
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Trevor M. Penning:

Chemical Carcinogenesis - new book

ISBN: 9781617379956

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many ca… More...

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Chemical Carcinogenesis
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Chemical Carcinogenesis - new book

ISBN: 9781617379956

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many ca… More...

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Chemical Carcinogenesis - Trevor M. Penning
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Trevor M. Penning:
Chemical Carcinogenesis - new book

ISBN: 9781617379956

Biomedicine; Cancer Research; Pharmacology/Toxicology Cancer, Cancer Research, Carcinogenesis, Chemical Books eBook, Springer Nature

  - Presenting the current advances in chemical carcinogenesis, this volume promotes the view that the chemical alteration of DNA is a route cause of many cancers. Topics include the multi-stage model of chemical carcinogenesis, exposure to major classes of h Shipping costs:zzgl. Versandkosten., plus shipping costs
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Chemical Carcinogenesis - Trevor M. Penning
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Trevor M. Penning:
Chemical Carcinogenesis - new book

2011, ISBN: 9781617379956

eBooks, eBook Download (PDF), 2011, [PU: Humana Press], Humana Press, 2011

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Details of the book - Chemical Carcinogenesis


EAN (ISBN-13): 9781617379956
ISBN (ISBN-10): 1617379956
Publishing year: 2011
Publisher: Humana Press
440 Pages
Language: eng/Englisch

Book in our database since 2008-06-07T00:24:02-04:00 (New York)
Detail page last modified on 2024-03-07T05:47:00-05:00 (New York)
ISBN/EAN: 9781617379956

ISBN - alternate spelling:
1-61737-995-6, 978-1-61737-995-6
Alternate spelling and related search-keywords:
Book author: penning, lonely planet


Information from Publisher

Author: Trevor M. Penning
Title: Current Cancer Research; Chemical Carcinogenesis
Publisher: Humana; Humana Press
440 Pages
Publishing year: 2011-03-03
Totowa; NJ; US
Printed / Made in
Language: English
212,93 € (DE)
243,00 CHF (CH)
Available
XVI, 440 p.

EA; E107; eBook; Nonbooks, PBS / Medizin/Nichtklinische Fächer; Onkologie; Verstehen; Cancer; Cancer Research; Carcinogenesis; Chemical; B; Cancer Research; Pharmacology/Toxicology; Cancer Biology; Pharmacology; Medicine; Pharmakologie; BB

This volume will provide a contemporary account of advances in chemical carcinogenesis. It will promote the view that it is chemical alteration of the DNA that is a route cause of many cancers. The multi-stage model of chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action will be a focal point. The balance between metabolic activation to form biological reactive intermediates and their detoxification, ensuing DNA-lesions and their repair will be profiled. It will describe the chemical changes that occur in DNA that result from endogenous insults including epigenetic changes that lead to gene silencing. It will describe major mechanisms of mutagenesis, affects on tumor suppressor genes and proto-oncogenes, and how cell-cycle check points can be by-passed by the "stealth-like" properties of chemical carcinogens. Environmental agents that can promote tumor formation will be discussed. The monograph will have wide appeal as a knowledge base for graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research.

1.      Historical Overview of Chemical Carcinogenesis

2.      Multistage Carcinogenesis

3.      Tobacco Smoke Carcinogens and Lung Cancer

4.      Mechanisms of Estrogen Carcinogenesis: Modulation by Botanical Natural Products

5.      Heterocyclic Amines: Potential Human Carcinogens

6.      Aflatoxins and Hepatocellular Carcinoma

7.      Metabolic Activation of Chemical Carcinogens

8.      Detoxication of  Chemical Carcinogens and Chemoprevention

9.      Covalent Polycyclic Aromatic Hydrocarbon-DNA Adducts, Carcinogenicity, Structure and Function

10.  Oxidation and Deamination of DNA by Endogenous Sources

11.  Lipid Peroxide-DNA Adducts

12.  Chemical Carcinogenesis and  Epigenetics

13.  Nucletoide Excision Repair From Bacteria to Humans: Structure-Function Studies

14.  Base Excision Repair: Role of DNA Polymerase b in Late Stage Base Excision Repair

-Alkylguanine-DNA alkyltransferase

16.  By-Pass DNA Polymerases

17.  Mutagenesis: The Outcome of Faulty Replication of DNA

18.  p53 and Ras-Mutation

Focuses of this volume: chemical carcinogenesis, exposure to major classes of human carcinogens and their mode-of-action, the balance between metabolic activation to form biological reactive intermediates and their detoxification, and environmental agents that can promote tumor formation

appeals to graduate students, post-doctoral fellows and faculty interested in this aspect of cancer causation and research



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9781617379949 Chemical Carcinogenesis (Current Cancer Research) (Penning)


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