ISBN: 9780792335252

This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. In prostate cancer, estramustine phosphate will likely play an expanding role. Co… More...

This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. In prostate cancer, estramustine phosphate will likely play an expanding role. Concepts, Mechanisms, and New Targets for Chemotherapy describes new interconnections between rationally designed and empirically discovered compounds. One route that has not been travelled previously is that of protein kinase C inhibition. This pathway may be exploited to give potent inhibitors, such as the bryostatins, now in clinical trial. A summary is given of the current status of topoisomerase, focusing on recent clinical advances with camptothecin analogs based on connecting empiricism with concepts of drug selectivity. Modification of existing therapies based on the pursuit of leads arising from mechanistic studies is also being applied clinically on a wide scale. Greater understanding should follow from the studies of reversal of the multidrug resistant phenotype, on the use of hydroxyurea to reverse resistance mediated by extrachromosomal DNA, and on various aspects of the fluoropyrimidine pathways. Successful applications of chemotherapy to the treatment of specific diseases include the growing applications of systemic therapy using various skin malignancies. In prostate cancer, estramustine phosphate will likely play an expanding role. Taxanes are restructuring treatment regimens in breast cancer, and high-dose strategies are described with peripheral blood progenitor autografting in the treatment of ovarian and breast cancers., Neu, Festpreisangebot, [LT: FixedPrice], EAN: 9780792335252, UPC: 9780792335252, Recommended Age Range: 0-12 months, Item Length: 23.4 cm, Publication Year: 1995, Type: Textbook, Format: Hardcover, Language: English, Publication Name: Concepts, Mechanisms, and New Targets for Chemotherapy, Item Height: 235mm, Item Width: 155mm, Subject: Medicine, Item Weight: 1160g, Number of Pages: 237 Pages, Springer<

1995, ISBN: 9780792335252

Editor: Muggia, Franco M. Springer, Hardcover, Auflage: 1995, 247 Seiten, Publiziert: 1995-12-31T00:00:01Z, Produktgruppe: Book, 1.16 kg, Books Global Store, Special Features, Books, Gene… More...

Editor: Muggia, Franco M. Springer, Hardcover, Auflage: 1995, 247 Seiten, Publiziert: 1995-12-31T00:00:01Z, Produktgruppe: Book, 1.16 kg, Books Global Store, Special Features, Books, General Medical Issues, Medical & Healthcare Practitioners, Health, Family & Lifestyle, Subjects, Oncology, Diseases & Disorders, Internal Medicine, Sensory & Therapeutic Gardens, Garden Styles, Gardening, Crafts, Hobbies & Home, Science, Nature & Maths, Medical Sciences A-Z, Medicine & Nursing, Scientific, Technical & Medical, Springer, 1995<

1995, ISBN: 9780792335252

Editor: Muggia, Franco M. Springer, Hardcover, Auflage: 1995, 247 Seiten, Publiziert: 1995-12-31T00:00:01Z, Produktgruppe: Book, 1.16 kg, Breast Cancer, Cancer, Diseases & Physical Ailmen… More...

Editor: Muggia, Franco M. Springer, Hardcover, Auflage: 1995, 247 Seiten, Publiziert: 1995-12-31T00:00:01Z, Produktgruppe: Book, 1.16 kg, Breast Cancer, Cancer, Diseases & Physical Ailments, Health, Fitness & Dieting, Subjects, Books, Prostate Disease, Gardening & Landscape Design, Crafts, Hobbies & Home, Oncology, Internal Medicine, Medicine, Medical Books, Clinical, Medicine & Health Sciences, New, Used & Rental Textbooks, Specialty Boutique, General, Springer, 1995<

1995, ISBN: 0792335252

[EAN: 9780792335252], Neubuch, [PU: Springer], New. In shrink wrap., Books