Stereoselective Synthesis of Drugs and Natural Products: Two Volume Set - First edition

EAN (ISBN-13): 9781118032176
ISBN (ISBN-10): 1118032179
Hardcover
Publishing year: 2013
Publisher: Wiley

Book in our database since 2014-02-26T15:50:30-05:00 (New York)
Detail page last modified on 2024-02-13T09:51:45-05:00 (New York)
ISBN/EAN: 9781118032176

ISBN - alternate spelling:
1-118-03217-9, 978-1-118-03217-6
Alternate spelling and related search-keywords:
Book author: vasyl andrushko, andrus, natalia
Book title: stereoselective synthesis, natura, stereo, drugs, stere

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Information from Publisher

Author: Vasyl Andrushko; Natalia Andrushko
Title: Stereoselective Synthesis of Drugs and Natural Products - Two Volume Set
Publisher: Wiley; John Wiley & Sons
1836 Pages
Publishing year: 2013-11-29
Weight: 4,830 kg
Language: English
540,00 € (DE)
Not available (reason unspecified)
268mm x 289mm x 101mm

SA; BB; Hardcover, Softcover / Chemie/Organische Chemie; Organische Chemie; Catalysis; Chemie; Chemistry; Katalyse; Organic Chemistry; Organische Chemie; Pharmaceutical & Medicinal Chemistry; Pharmazeutische u. Medizinische Chemie; Katalyse; Pharmazeutische u. Medizinische Chemie; Organische Chemie

Preface List of contributors List of symbols and abbreviations PART 1: GENERAL METHODS AND STRATEGIES Chapter 1: Principles, concepts and strategies of stereoselective synthesis Vasyl Andrushko and Natalia Andrushko Chapter 2: Chiral auxiliaries in drug synthesis Stanley Chang, Shira D. Halperin, Jarod Moore and Robert Britton Chapter 3: Solid-phase organic synthesis of drugs and natural products Peter J. H. Scott Chapter 4: Asymmetric phase-transfer catalysis Kohsuke Ohmatsu, Daisuke Uraguchi, and Takashi Ooi Chapter 5: Microwave-assisted stereoselective synthesis Yoann Coquerel, Evelina Colacino, Jean Rodriguez, Jean Martinez and Frédéric Lamaty Chapter 6: Application of micro reactor methodology for organic synthesis Paul Watts and Charlotte Wiles PART 2: STEREOSELECTIVE SYNTHESIS BY BOND FORMATION 2.1. STEREOSELECTIVE METHODS FOR C-C BOND FORMATION Chapter 7: Asymmetric alpha-alkylation of aldehydes, ketones and carboxylic acids Mark C. Kohler, Sarah E. Wengryniuk, and Don M. Coltart Chapter 8: Asymmetric aldol reactions in the total syntheses of natural products Seijiro Hosokawa Chapter 9: Asymmetric Michael addition and related reactions Pengfei Li, Jun Wang and Fuk Yee Kwong Chapter 10: Construction of polypropionate fragments in natural product synthesis Maris Turks, Sylvain Laclef and Pierre Vogel Chapter 11: Organocatalytic conjugate addition in stereoselective synthesis Adrien Quintard and Alexandre Alexakis Chapter 12: Stereoselective Nozaki-Hiyama-Kishi reaction Pat Guiry and Gráinne Hargaden Chapter 13: Transition-metal-catalyzed asymmetric C-C cross-couplings in stereoselective synthesis Vasiliki Sarli Chapter 14: Asymmetric hydroformylation, hydroxy- and alkoxycarbonylation for stereoselective synthesis Jamie T. Durrani and Matthew L. Clarke Chapter 15: Intramolecular oxycarbonylation in stereoselective synthesis Tibor Gracza Chapter 16: Stereoselective cycloaddition reactions Tae-Kyung Lee and Jung-Mo Ahn Chapter 17: Sigmatropic rearrangements in stereoselective synthesis Brinton Seashore-Ludlow and Peter Somfai Chapter 18: Ring contraction reactions in the total synthesis of biologically active natural products Luiz F. Silva Jr. Chapter 19: Electrocyclic reactions in stereoselective synthesis Marcus A. Tius Chapter 20: Transannular cyclization in natural product total synthesis Jiong Yang and Haoran Xue Chapter 21: Cascade reactions in stereoselective synthesis Bor-Cherng Hong and Nitin S. Dange Chapter 22: Sulfur dioxide: a powerful tool for the stereoselective construction of C-C bonds Pierre Vogel, Dean Markovic and Mâris Turks Chapter 23: Transition metal C-H activation: application to stereoselective synthesis of natural products and drugs Mickaël Jean and Pierre van de Weghe Chapter 24: Metathesis reactions in drug and natural product synthesis Akio Saito, Yuji Hanzawa Chapter 25: Radicals in stereoselective C-C bond formation Josep Bonjoch, Ben Bradshaw and Faïza Diaba Chapter 26: Trifluoromethyl (CF3) group insertion methods in stereoselective synthesis Tsutomu Konno Chapter 27: Stereoselective organocatalyzed C-C bond-forming reactions Kazuo Nagasawa and Koji Yasui Chapter 28: Enzyme-catalysed stereoselective C-C bond formation reactions in total syntheses Adeline Ranoux and Ulf Hanefeld 2.2. STEREOSELECTIVE METHODS FOR C-H BOND FORMATION Chapter 29: Stereoselective hydrogenation of C=C bonds: application to drug and natural product synthesis Natalia Andrushko and Vasyl Andrushko Chapter 30: Asymmetric hydrogenation of C=O and C=N bonds in stereoselective synthesis Natalia Andrushko and Vasyl Andrushko Chapter 31: Asymmetric protonation of carbanions and polar double bonds: application to total syntheses Thomas Poisson and Shu Kobayashi Chapter 32: Organocatalytic reduction in stereoselective synthesis Felix Kortmann and Adriaan Minnaard Chapter 33: Biocatalytic asymmetric reduction of C=O and activated C=C bonds in stereoselective synthesis Tomoko Matsuda, Rio Yamanaka and Kaoru Nakamura 2.3. STEREOSELECTIVE METHODS FOR C-O BOND FORMATION Chapter 34: Transition-metal-catalyzed stereoselective oxidations in drug and natural product synthesis Alessandro Scarso and Giorgio Strukul Chapter 35: Asymmetric epoxidation in stereoselective synthesis Zhicai Yang Chapter 36: Biocatalytic asymmetric oxidations in stereoselective synthesis Anett Schallmey, Pablo Dominguez de Maria and Paula Bracco Chapter 37: Ether transfer methodology: application to the synthesis of polyketide natural products Eric Stefan and Richard E. Taylor Chapter 38: Stereoselective formation of 2-deoxyglycosidic bonds in biologically active natural products Daisuke Takahashi and Kazunobu Toshima 2.4. STEREOSELECTIVE METHODS FOR C-N BOND FORMATION Chapter 39: Asymmetric hydroamination and reductive amination in total synthesis Manas K. Ghorai, Deo Prakash Tiwari and Aditya Bhattacharyya Chapter 40: Carboamination and alkylative cyclization with C-N bond formation in stereoselective syntheses Manas K. Ghorai, Sandipan Halder and Sauvik Samanta Chapter 41: Cycloadditions with stereoselective C-N bond formation in total syntheses Guillaume Vincent 2.5. STEREOSELECTIVE FORMATION OF OTHER C-HETEROATOM AND OTHER BONDS Chapter 42: Stereoselective halogenations Chong Kiat Tan, Yi Zhao, Jing Zhou and Ying-Yeung Yeung Chapter 43: Stereoselective synthesis of halogenated natural products Takehiko Yoshimitsu Chapter 44: Asymmetric fluorination methods: application in the stereoselective synthesis of fluorinated drugs Vincent Bizet and Dominique Cahard Chapter 45: Enzymatic halogenation in stereoselective synthesis Cormac D. Murphy and Benjamin R. Clark Chapter 46: Stereoselective carbon-sulfur (C-S) bond formation Kyungsoo Oh Chapter 47: Stereoselective methods for carbon-phosphorus (C-P) bond formation Marcin Kalek and Jacek Stawinski Chapter 48: Transition-metal-catalyzed asymmetric sulfoxidation in drug and natural product synthesis Alessandro Scarso and Giorgio Strukul PART 3: METHODS OF ANALYSIS AND CHIRAL SEPARATION Chapter 49: NMR-Spectroscopy in drug and natural product analysis Stanisuaw Witkowski and Iwona Wawer Chapter 50: Determination of enantiomeric purity and absolute configuration by NMR spectroscopy Thomas J. Wenzel Chapter 51: Solid-state NMR spectroscopy in drug design and discovery David A. Middleton and Simon G. Patching Chapter 52: Capillary electrophoresis in chiral separations Ans Hendrickx, Debby Mangelings and Yvan Vander Heyden Chapter 53: Determination of absolute configuration using chiroptical methods Joao Marcos Batista, Jr. Chapter 54: Chiral chromatographic methods in the analysis and purification of enantiomers Arnau Novell and Cristina Minguillón Chapter 55: X-Ray crystallography and 1H NMR anisotropy methods for determination of absolute configurations Nobuyuki Harada Chapter 56: Crystallization based separation of enantiomers Yaling Wang and Alex Chen Chapter 57: Enzymatic dynamic kinetic resolution in stereoselective synthesis Francisca Rebolledo, Javier González-Sabín, and Vicente Gotor Subject index