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Strategies for Organic Drug Synthesis and Design - Daniel Lednicer
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Strategies for Organic Drug Synthesis and Design - hardcover

2008, ISBN: 0470190396

[EAN: 9780470190395], Nieuw boek, [SC: 14.25], [PU: Wiley-Interscience], SCIENCE / CHEMISTRY GENERAL, nach der Bestellung gedruckt Neuware -Your Blueprint for Successful Drug Synthesis an… More...

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Strategies for Organic Drug Synthesis and Design by Daniel Lednicer Hardcover | Indigo Chapters
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ISBN: 9780470190395

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1… More...

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Strategies for Organic Drug Synthesis and Design
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This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1… More...

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Strategies for Organic Drug Synthesis and Design 2e
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This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1… More...

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Strategies for Organic Drug Synthesis and Design
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This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1… More...

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Strategies for Organic Drug Synthesis and Design by Daniel Lednicer Hardcover | Indigo Chapters
Author:
Title:
ISBN:

9780470190395


Your Blueprint for Successful Drug Synthesis and Design Guiding readers through tested-and-proven strategies for designing and conducting drug synthesis, this Second Edition features the latest developments in the field, including new examples of drug synthesis from major pharmaceutical companies. Examples are selected from the multivolume work, titled The Organic Chemistry of Drug Synthesis. This new, expanded edition focuses on the organic chemistry used for drug preparation. Drugs have been selected based on the illustrative value of the chemistry used for their synthesis. Structures in chemical schemes have been carefully drawn to clarify individual reactions. Brief discussions of medicinal chemistry provide readers with a snapshot of the activity and the mechanism of action of various drugs. Salient principles of drug action are presented in capsule form at appropriate points. In addition, the claimed therapeutic effects of each pharmaceutical agent are noted along with the discussion of its preparation. Strategies for Organic Drug Synthesis and Design has been updated with a host of new drugs, including drugs that address new therapeutic areas and drugs developed with the use of novel chemistry. These include: * Tubulin Inhibitors (Taltobulin) * Antimalarial arteflene * Neuraminidase Antivirals (Zanamavir, Oseltamavir, and Peramavir) * COX-2 Inhibitor NSAIDs (Celecoxib, Cimicoxib, and Valdecoxib) Written by an experienced and successful author and pharmaceutical scientist, this book meets the needs of the growing community of researchers in pharmaceutical R&D as well as medical professionals who need to understand the design and synthesis of pharmaceutical agents. It is also recommended as a graduate-level medicinal chemistry textbook.

Details of the book - Strategies for Organic Drug Synthesis and Design by Daniel Lednicer Hardcover | Indigo Chapters


EAN (ISBN-13): 9780470190395
ISBN (ISBN-10): 0470190396
Hardcover
Publishing year: 2008
Publisher: Daniel Lednicer
682 Pages
Weight: 1,089 kg
Language: eng/Englisch

Book in our database since 2008-08-30T09:18:19-04:00 (New York)
Detail page last modified on 2023-04-14T19:34:13-04:00 (New York)
ISBN/EAN: 9780470190395

ISBN - alternate spelling:
0-470-19039-6, 978-0-470-19039-5
Alternate spelling and related search-keywords:
Book title: strategies for organic drug synthesis and design, sign and design, design and strategy organic synthesis, organic syntheses, edition

Information from Publisher

Author: Daniel Lednicer
Title: Strategies for Organic Drug Synthesis and Design
Publisher: John Wiley & Sons
700 Pages
Publishing year: 2008-11-14
Weight: 1,086 kg
Language: English
175,00 € (DE)
No longer receiving updates
164mm x 238mm x 36mm

BB; gebunden; Hardcover, Softcover / Chemie/Organische Chemie; Organische Chemie; Chemie; Chemische Synthese; Wirkstoffforschung u. -entwicklung; Drug Discovery & Development; Arzneimittelentwicklung; Methods - Synthesis & Techniques; Pharmakologie u. Pharmazeutische Medizin; Medical Science; Medizin; Organische Chemie / Methoden, Synthesen, Verfahren; Pharmacology & Pharmaceutical Medicine; Chemistry; Pharmakologie u. Pharmazeutische Medizin; Wirkstoffforschung u. -entwicklung; Organische Chemie / Methoden, Synthesen, Verfahren

Preface 1. PROSTAGLANDINS, PEPTIDOMIMETIC COMPOUNDS, AND RETINOIDS. 1.1 Prostaglandnis. 1.2 Peptidonimetic Compounds. 1.3 Retinoids. 1.4 A Miscellaneous Drug. References. 2. DRUG BASED ON A SUBSTITUTED BENZENE RING 2.1 Arylethanolamines. 2.2 Aryloxypropanolamines. 2.3 Arylsulfonic Acid Derivatives. 2.4 Arylacetic and Arylpropionic Acids. 3. INDENES, NAPHTHALENES AND OTHER POLYCYCLIC AROMATIC COMPOUNDS 3.1 Indenes. 3.2 Naphthalenes. 3.3 Partly Reduced Naphthalenes. 3.4 Tricyclic Compounds. References. 4. STEROIDS; PART 1: ESTRANES, GONANES, AND ANDROSTANES 4.1 Introduction. 4.2 Steroid Starting Materials. 4.3 Estranes. 4.4 Gonanes, the 19-nor Steroids. 4.5 Androstanes. References. 5. STEROIDS; PART 2: COMPOUNDS RELATED TO PROGESTERONE, CORTISONE, AND CHOLESTEROL. 5.1 Introduction. 5.2 Progestins. 5.3 Corticosteroids. 5.4 Compounds Derived from Cholesterol. References. 6. NONSTEROIDAL SEX HORMONES AND THEIR ANTAGONISTS 6.1 Introduction. 6.2 Estrogens. References. 7. OPIOID ANAlGESICS 7.1 Introduction 7.2 Drugs Derived from Morphine. 7.3 Compounds Prepared from Thebaine. 7.4 Morphinans. 7.5 Benzomorphans. 7.6 Analgesics Based on Nonfused Piperidines. References. 8. DRUGS BASED ON FIVE-MEMBERED HETEROCYCLES 8.1 Introduction. 8.2 Rings that Contain One Heteroatom. 8.3 Rings that Contain Two Heteroatoms. 8.4 Rings that Contains Three or More Heteroatoms. References. 9. DRUGS BASED ON SIX-MEMBERED HETEROCYCLES. 9.1 Rings that Contain One Heteroatom. 9.2 Rings that Contain Two Heteroatoms. 9.3 Rings Containing Three Heteroatoms: The Triazines. References. 10. FIVE-MEMBERED HETEROCYCLES FUSED TO A BENZENE RING. 10.1 Compounds that Contain One Heteroatom. 10.2 Compounds that Contain Two Heteroatoms. 10.3 Compounds that Contain Three Heteroatoms. References. 11. SIX-MEMBERED HETEROCYCLES FUSED TO A BENZENE RING 11.1 Compounds that Contain One Heteroatom. 11.2 Compounds that Contain Two Heteroatoms. 11.3 Compounds that Contain Three Heteroatoms. References. 12. SEVEN-MEMBERED HETEROCYCLIC FUSED TO BENZENE. 12.1 Compounds with a Single Heterocyclic Atom. 12.2 Compounds with Two Heteroatoms. References. 13. HETEROCYLES FUSED TO TWO AROMATIC RINGS 13.1 Compounds Containing a Single Heteroatom. 13.2 Compounds Containing Two Heteroatoms. 13.3 Pyridine-Based Fused Tricyclic Compounds. References. 14. BETA LACTAM ANTIBIOTICS 14.1 Penicillins. 14.2 Cephalosporins. 14.3 Monobactams. References. 15. HETEROCYCLES FUSED TO OTHER HETEROCYCLIC RINGS. 15.1 Two Fused Five-Membered Rings. 15.2 Five-Membered Heterocycles Fused to Six-Membered Rings. 15.3 Two Fused Six-Membered Rings. 15.4 Heterodiazepines. 15.5 Heterocyclic Compounds with Three or More Rings. References. Subject Index. Reaction Index. Cross Index of Biological Activities.
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