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Heart Failure - new book

ISBN: 9780470015971

Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associat… More...

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Heart Failure : Molecules, Mechanisms and Therapeutic Targets by Novartis Foundation Symposium - Novartis Foundation Symposium
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Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associat… More...

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Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia)
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Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia) - First edition

2006

ISBN: 9780470015971

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Editor: Bock, Gregory R. Editor: Goode, Jamie A. Wiley, Hardcover, Auflage: 1, 302 Seiten, Publiziert: 2006-07-28T00:00:01Z, Produktgruppe: Book, 0.59 kg, Books Global Store, Special Feat… More...

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Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia)
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Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia) - First edition

2006, ISBN: 9780470015971

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Editor: Bock, Gregory R. Editor: Goode, Jamie A. Wiley, Hardcover, Auflage: 1, 302 Seiten, Publiziert: 2006-07-28T00:00:01Z, Produktgruppe: Book, 0.59 kg, Books Global Store, Special Feat… More...

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ISBN: 9780470015971

1st Edition, by Gregory R. Bock; Jamie A. Goode, PRINT ISBN: 9780470015971 E-TEXT ISBN: 9780470029329 Additional ISBNs: 9780470029336 Wiley Professional Reference & Trade (Wiley K&L) eBoo… More...

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Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia)
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ISBN:

9780470015971


Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress has been made in unravelling the cellular circuitry involved in cardiac failure, as well as in normal cardiac growth, development and apoptosis. This work has revealed new and unexpected therapeutic targets in the heart. In addition, advances in understanding the role of stem cells in cardiac physiology have suggested strategies for cardiac repair and regeneration once thought impossible. This book describes the work of leading investigators studying the basic mechanisms of cardiac growth, function and dysfunction. There are also exciting contributions from researchers developing novel therapeutic strategies for cardiac disease. The unique feature is the discussions amongst the contributors, which always return to the same basic problem: how can new data from biological studies be used to design novel therapies for the treatment of cardiac dysfunction following myocardial infarction, hypertension and other disorders? With its strong emphasis on translational research, this book will appeal to both scientists and clinicians interested in diminishing the impact of the current epidemic of cardiac diseases.

Details of the book - Heart Failure: Molecules, Mechanisms and Therapeutic Targets: 274 (Novartis Foundation Symposia)


EAN (ISBN-13): 9780470015971
ISBN (ISBN-10): 0470015977
Hardcover
Publishing year: 2006
Publisher: Wiley
291 Pages
Weight: 0,608 kg
Language: eng/Englisch

Book in our database since 2007-04-12T02:08:27-04:00 (New York)
Detail page last modified on 2023-10-19T01:41:07-04:00 (New York)
ISBN/EAN: 9780470015971

ISBN - alternate spelling:
0-470-01597-7, 978-0-470-01597-1
Alternate spelling and related search-keywords:
Book author: greg goode, john main, foundation
Book title: heart failure, molecules, upon this foundation, look into the heart, heart will and more, take heart, target the heart, novartis, 274

Information from Publisher

Title: Novartis Foundation Symposium; Heart Failure - Molecules, Mechanisms and Therapeutic Targets. No. 274
Publisher: John Wiley & Sons
302 Pages
Publishing year: 2006-07-28
Weight: 0,614 kg
Language: English
199,00 € (DE)
No longer receiving updates
185mm x 235mm x 19mm

BB; gebunden; Hardcover, Softcover / Biologie/Mikrobiologie; Biologie, Biowissenschaften; Biotechnologie; Biotechnologie i. d. Biowissenschaften; Cardiovascular Disease; Biotechnology; Life Sciences; Medizin; Medical Science; Biowissenschaften; Zell- u. Molekularbiologie; Kardiovaskuläre Erkrankungen; Cell & Molecular Biology; Kardiovaskuläre Erkrankungen; Zell- u. Molekularbiologie; Biotechnologie i. d. Biowissenschaften

Introduction (Eric N. Olson). Control of cardiac hypertrophy and heart failure by histone acetylation/deacetylation (Eric N. Olson, Johannes Backs and Timothy A. McKinsey). Discussion. A novel mechanism of mechanical stress-induced hypertrophy (Hiroshi Akazawa, Yunzeng Zou and Issei Komuro). Discussion. Controlling cardiomyocyte survival (N. de Jonge, M. J. Goumans, Daan Lips, Rutger Hassink, Eva J. Vlug, Roy van der Meel, Christopher Donald Emmerson, Joppe Nijman, Leon de Windt and Pieter A. Doevendans). Discussion. Mechanisms of angiotensin II-dependent progression to heart failure (Mona Nemer, Nassim Dali-Youcef, Hao Wang, Anne Aries and Pierre Paradis). Discussion. Alterations in myocardial gene expression as a basis for cardiomyopathies and heart failure (Matthew R. Taylor and Michael R. Bristow). Discussion. Role of the insulin-like growth factor 1 (IGF1)/phosphoinositide-3-kinase (PI3K) pathway mediating physiological cardiac hypertrophy (Julie R. McMullen and Seigo Izumo). Discussion. Role of Akt in cardiac growth and metabolism(Anthony J. Muslin and Brian DeBosch). Discussion. Novel therapy for heart failure and exercise-induced ventricular tachycardia based on 'fixing' the leak in ryanodine receptors (Andrew R. Marks). Discussion. General discussion I. Phospholamban as a therapeutic modality in heart failure (Guoxiang Chu and Evangelia G. Kranias). Discussion. Sarcomere protein gene mutations and inherited heart disease: a b-cardiac myosin heavy chain mutation causing endocardial fibroelastosis and heart failure (Mitsuhiro Kamisago, Joachim P. Schmitt, Dennis McNamara, Christine Seidman and Jonathan G. Seidman). Discussion. The cardiomyocyte cell cycle (Pascal J. E. Lafontant and Loren J. Field). Discussion. Restoration of cardiac function with progenitor cells (Carmen Urbich, Lothar Rössig and Stefanie Dimmeler). Discussion. Signalling pathways in cardiac regeneration (Maria Paola Santini, Nadine Winn and Nadia Rosenthal). Discussion. Beyond small molecule drugs for heart failure: prospects for gene therapy (Kenneth R. Chien). Discussion. Dual roles of telomerase in cardiac protection and repair (Michael D. Schneider). Discussion. Final general discussion. Closing remarks: historical perspective (Arnold M. Katz). Index of contributors. Subject index.

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