2009, ISBN: 9780123847447

Reliable Lab Solutions, eBooks, eBook Download (EPUB,PDF), Auflage, Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. … More...

Reliable Lab Solutions, eBooks, eBook Download (EPUB,PDF), Auflage, Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents. Contemporary Enzyme Kinetics and Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, 249, 308 and 354 of Methods in Enzymology. The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery of these topics. The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design.Of the seventeen chapters presented in this new edition, ten did not previously appear in the first edition. Transient kinetic approaches to enzyme mechanisms Designing initial rate enzyme assay Deriving initial velocity and isotope exchange rate equations Plotting and statistical methods for analyzing rate data Cooperativity in enzyme function Reversible enzyme inhibitors as mechanistic probes Transition-state and multisubstrate inhibitors Affinity labeling to probe enzyme structure and function Mechanism-based enzyme inactivators Isotope exchange methods for elucidating enzymatic catalysis Kinetic isotope effects in enzyme catalysis Site-directed mutagenesis in studies of enzyme catalysis, [PU: Elsevier Science], Seiten: 704, Elsevier Science, 2009<

ISBN: 9780123847447

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly… More...

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents.Contemporary Enzyme Kinetics and Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, 249, 308 and 354 of Methods in Enzymology. The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery of these topics.The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design. Of the seventeen chapters presented in this new edition, ten did not previously appear in the first edition.Transient kinetic approaches to enzyme mechanismsDesigning initial rate enzyme assayDeriving initial velocity and isotope exchange rate equationsPlotting and statistical methods for analyzing rate dataCooperativity in enzyme functionReversible enzyme inhibitors as mechanistic probesTransition-state and multisubstrate inhibitorsAffinity labeling to probe enzyme structure and functionMechanism-based enzyme inactivatorsIsotope exchange methods for elucidating enzymatic catalysisKinetic isotope effects in enzyme catalysisSite-directed mutagenesis in studies of enzyme catalysis; PDF; Scientific, Technical and Medical > Biology, life sciences > Biochemistry, Elsevier Science<

ISBN: 9780123847447

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly… More...

Kinetic studies of enzyme action provide powerful insights into the underlying mechanisms of catalysis and regulation. These approaches are equally useful in examining the action of newly discovered enzymes and therapeutic agents.Contemporary Enzyme Kinetics and Mechanism, Second Edition presents key articles from Volumes 63, 64, 87, 249, 308 and 354 of Methods in Enzymology. The chapters describe the most essential and widely applied strategies. A set of exercises and problems is included to facilitate mastery of these topics.The book will aid the reader to design, execute, and analyze kinetic experiments on enzymes. Its emphasis on enzyme inhibition will also make it attractive to pharmacologists and pharmaceutical chemists interested in rational drug design. Of the seventeen chapters presented in this new edition, ten did not previously appear in the first edition.Transient kinetic approaches to enzyme mechanismsDesigning initial rate enzyme assayDeriving initial velocity and isotope exchange rate equationsPlotting and statistical methods for analyzing rate dataCooperativity in enzyme functionReversible enzyme inhibitors as mechanistic probesTransition-state and multisubstrate inhibitorsAffinity labeling to probe enzyme structure and functionMechanism-based enzyme inactivatorsIsotope exchange methods for elucidating enzymatic catalysisKinetic isotope effects in enzyme catalysisSite-directed mutagenesis in studies of enzyme catalysis; PDF; Scientific, Technical and Medical > Biology, life sciences > Biochemistry, Elsevier Science<

2009, ISBN: 9780123847447

Editor: Purich, Daniel L. Academic Press, Kindle Edition, Auflage: 3, 1224 Seiten, Publiziert: 2009-10-24T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Biochemistry, Biological Sci… More...

Editor: Purich, Daniel L. Academic Press, Kindle Edition, Auflage: 3, 1224 Seiten, Publiziert: 2009-10-24T00:00:00.000Z, Produktgruppe: Digital Ebook Purchas, Biochemistry, Biological Sciences, Science & Math, Subjects, Books, Molecular Biology, Biophysics, Pharmacology, Medical Books, Specialty Boutique, Kindle eBooks, Categories, Kindle Store, Basic Science, Medical eBooks, Basic Sciences, Medicine & Health Sciences, Kindle eTextbooks, Specialty Stores, Biology & Life Sciences, Science & Mathematics, English Language Store, Core Detail Page Stripe Ver.2 1-2016, Format: Kindle eBook, Academic Press, 2009<