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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Herausgegeben von Lash, Lawrence H.
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Herausgegeben von Lash, Lawrence H.:

Drug Metabolism and Transport: Molecular Methods and Mechanisms - Paperback

2010, ISBN: 9781617374944

[ED: Softcover], [PU: Springer, Berlin], A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. Remarkable advances in molecular and cell biology and the development of novel in vitro model systems have greatly expanded our knowledge of the processes involved in metabolism and transport and led to numerous new therapeutic approaches. In Drug Metabolism and Transport: Molecular Methods and Mechanisms, well-established investigators describe their best experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low-molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. The strategies detailed for transport phenomena cover the multidrug resistance proteins, the reduced folate carrier, the plasma membrane, and mitochondrial glutathione transporters, and can be applied to numerous other transport systems. Many chapters contain step-by-step methods for investigating metabolism and transport.Insightful and broad-ranging, Drug Metabolism and Transport: Molecular Methods and Mechanisms offers novice and experienced investigators alike a highly useful compendium of key strategies and approaches to successful research on drug metabolism and transport pathways.2010. x, 388 S. 110 SW-Abb. 229 mmVersandfertig in über 4 Wochen, [SC: 0.00], Neuware, gewerbliches Angebot

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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Springer
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Drug Metabolism and Transport: Molecular Methods and Mechanisms - new book

2010, ISBN: 9781617374944

ID: 660789187

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. Remarkable advances in molecular and cell biology and the development of novel in vitro model systems have greatly expanded our knowledge of the processes involved in metabolism and transport and led to numerous new therapeutic approaches. In Drug Metabolism and Transport: Molecular Methods and Mechanisms, well-established investigators describe their best experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low-molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy. The strategies detailed for transport phenomena cover the multidrug resistance proteins, the reduced folate carrier, the plasma membrane, and mitochondrial glutathione transporters, and can be applied to numerous other transport systems. Many chapters contain step-by-step methods for investigating metabolism and transport. Insightful and broad-ranging, Drug Metabolism and Transport: Molecular Methods and Mechanisms offers novice and experienced investigators alike a highly useful compendium of key strategies and approaches to successful research on drug metabolism and transport pathways. Molecular Methods and Mechanisms Bücher > Fremdsprachige Bücher > Englische Bücher Taschenbuch 09.11.2010, Springer, .201

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Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology) - Lawrence H. Lash (Editor)
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Lawrence H. Lash (Editor):
Drug Metabolism and Transport: Molecular Methods and Mechanisms (Methods in Pharmacology and Toxicology) - Paperback

ISBN: 9781617374944

Hardcover, ID: 598699068

Humana Press. Softcover reprint of hardcover 1. Paperback. New. Buy with confidence. Excellent Customer Service & Return policy. Ships Fast. Expedite Shipping Available., Humana Press

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Drug Metabolism and Transport: Molecular Methods and Mechanisms - Lawrence H. Lash
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Lawrence H. Lash:
Drug Metabolism and Transport: Molecular Methods and Mechanisms - Paperback

ISBN: 9781617374944

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Drug Metabolism and Transport: Molecular Methods and Mechanisms Drug-Metabolism-and-Transport~~Lawrence-H-Lash Medicine>Health Professions>Pharmacology Paperback, Springer-Verlag New York, LLC

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Drug Metabolism and Transport - Lawrence H. Lash
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Lawrence H. Lash:
Drug Metabolism and Transport - Paperback

2010, ISBN: 9781617374944

ID: 16179227

1st ed. Softcover of orig. ed. 2005, Softcover, Buch, [PU: Humana Press Inc.]

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Details of the book
Drug Metabolism and Transport: Molecular Methods and Mechanisms
Author:

Herausgegeben von Lash, Lawrence H.

Title:

Drug Metabolism and Transport: Molecular Methods and Mechanisms

ISBN:

1617374946

A compendium of proven experimental approaches and strategies for studying the bioactivation, detoxification, tissue distribution, and elimination of xenobiotics in the metabolism and/or transport of various chemicals. The authors address several of the major drug metabolizing systems, including the cytochrome P450 family, flavin-containing monooxygenases, glutathione, S-transferase, glucuronidation, N-acetylation, and sulfotransferases. Additional chapters present novel approaches to the study of: signaling pathways in the regulation of drug metabolism enzymes, how the modulation of thiols and other low molecular-weight cofactors can alter drug metabolism, and how modulation of drug metabolism pathways can influence antiviral therapy.

Details of the book - Drug Metabolism and Transport: Molecular Methods and Mechanisms


EAN (ISBN-13): 9781617374944
ISBN (ISBN-10): 1617374946
Hardcover
Paperback
Publishing year: 2010
Publisher: SPRINGER VERLAG GMBH
400 Pages
Weight: 0,585 kg
Language: eng/Englisch

Book in our database since 21.10.2011 19:46:36
Book found last time on 17.11.2016 20:44:25
ISBN/EAN: 1617374946

ISBN - alternate spelling:
1-61737-494-6, 978-1-61737-494-4

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